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Trastuzumab treatment improves brain metastasis outcomes through control and durable prolongation of systemic extracranial disease in HER2-overexpressing breast cancer patients

In patients with human epidermal growth factor receptor-2 (HER2)-overexpressing breast cancer, treatment with trastuzumab has been shown to markedly improve the outcome. We investigated the role of trastuzumab on brain metastasis (BM) in HER2-positive breast cancer patients. From 1999 to 2006, 251 p...

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Detalles Bibliográficos
Autores principales: Park, Y H, Park, M J, Ji, S H, Yi, S Y, Lim, D H, Nam, D H, Lee, J-I, Park, W, Choi, D H, Huh, S J, Ahn, J S, Kang, W K, Park, K, Im, Y-H
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2661774/
https://www.ncbi.nlm.nih.gov/pubmed/19240719
http://dx.doi.org/10.1038/sj.bjc.6604941