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A noncoding RNA gene on chromosome 10p15.3 may function upstream of hTERT

BACKGROUND: We attempted to clone candidate genes on 10p14–15 which may regulate hTERT expression, through exon trapping using 3 BAC clones covering the region. After obtaining 20 exons, we examined the function of RGM249 (RGM: RNA gene for miRNAs) we cloned from primary cultured human hepatocytes a...

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Detalles Bibliográficos
Autores principales: Miura, Norimasa, Sato, Reina, Tsukamoto, Tomoe, Shimizu, Mika, Kabashima, Hiroko, Takeda, Miho, Takahashi, Shunsaku, Harada, Tomomi, West, James E, Drabkin, Harry, Mejia, Jose E, Shiota, Goshi, Murawaki, Yoshikazu, Virmani, Arvind, Gazdar, Adi F, Oshimura, Mitsuo, Hasegawa, Junichi
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2661890/
https://www.ncbi.nlm.nih.gov/pubmed/19187532
http://dx.doi.org/10.1186/1471-2199-10-5