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Position dependent mismatch discrimination on DNA microarrays – experiments and model

BACKGROUND: The propensity of oligonucleotide strands to form stable duplexes with complementary sequences is fundamental to a variety of biological and biotechnological processes as various as microRNA signalling, microarray hybridization and PCR. Yet our understanding of oligonucleotide hybridizat...

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Detalles Bibliográficos
Autores principales: Naiser, Thomas, Kayser, Jona, Mai, Timo, Michel, Wolfgang, Ott, Albrecht
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2661940/
https://www.ncbi.nlm.nih.gov/pubmed/19046422
http://dx.doi.org/10.1186/1471-2105-9-509