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High-throughput chromatin information enables accurate tissue-specific prediction of transcription factor binding sites

In silico prediction of transcription factor binding sites (TFBSs) is central to the task of gene regulatory network elucidation. Genomic DNA sequence information provides a basis for these predictions, due to the sequence specificity of TF-binding events. However, DNA sequence alone is an impoveris...

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Detalles Bibliográficos
Autores principales: Whitington, Tom, Perkins, Andrew C., Bailey, Timothy L.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2662491/
https://www.ncbi.nlm.nih.gov/pubmed/18988630
http://dx.doi.org/10.1093/nar/gkn866