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GRIM-19 inhibits v-Src-induced cell motility by interfering with cytoskeletal restructuring

GRIM-19 (Gene associated with Retinoid-Interferon-induced Mortality 19) is a novel tumor suppressor regulated by Interferon/retinoid combination. We have recently shown that GRIM-19 inhibits v-Src-induced oncogenic transformation and metastatic behavior of cells. Oncogenic v-Src induces cell motilit...

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Detalles Bibliográficos
Autores principales: Sun, Peng, Nallar, Shreeram C., Kalakonda, Sudhakar, Lindner, Daniel J., Martin, Stuart S., Kalvakolanu, Dhananjaya V.
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2662763/
https://www.ncbi.nlm.nih.gov/pubmed/19151760
http://dx.doi.org/10.1038/onc.2008.480