The high affinity selectin glycan ligand C2-O-sLe(x )and mRNA transcripts of the core 2 β-1,6-N-acetylglusaminyltransferase (C2GnT1) gene are highly expressed in human colorectal adenocarcinomas

BACKGROUND: The metastasis of cancer cells and leukocyte extravasation into inflamed tissues share common features. Specialized carbohydrates modified with sialyl Lewis x (sLe(x)) antigens on leukocyte membranes are ligands for selectin adhesion molecules on activated vascular endothelial cells at i...

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Detalles Bibliográficos
Autores principales: St Hill, Catherine A, Farooqui, Mariya, Mitcheltree, Gregory, Gulbahce, H Evin, Jessurun, Jose, Cao, Qing, Walcheck, Bruce
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2662873/
https://www.ncbi.nlm.nih.gov/pubmed/19267921
http://dx.doi.org/10.1186/1471-2407-9-79

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2662873/
https://www.ncbi.nlm.nih.gov/pubmed/19267921
http://dx.doi.org/10.1186/1471-2407-9-79

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