Cargando…
A Grafting Strategy for the Design of Improved G-Quadruplex Aptamers and High-Activity DNAzymes
Nucleic acid aptamers are generally obtained by in vitro selection. Some have G-rich consensus sequences with ability to fold into the four-stranded structures known as G-quadruplexes. A few G-quadruplex aptamers have proven to bind hemin to form a new class of DNAzyme with the peroxidase-like activ...
| Autores principales: | , , |
|---|---|
| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2009
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2663033/ https://www.ncbi.nlm.nih.gov/pubmed/19357767 http://dx.doi.org/10.1371/journal.pone.0005126 |