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Losartan Decreases p42/44 MAPK Signaling and Preserves LZ+ MYPT1 Expression
Heart failure is associated with impairment in nitric oxide (NO) mediated vasodilatation, which has been demonstrated to result from a reduction in the relative expression of the leucine zipper positive (LZ+) isoform of the myosin targeting subunit (MYPT1) of myosin light chain phosphatase. Further,...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
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Public Library of Science
2009
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2663051/ https://www.ncbi.nlm.nih.gov/pubmed/19357768 http://dx.doi.org/10.1371/journal.pone.0005144 |