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Losartan Decreases p42/44 MAPK Signaling and Preserves LZ+ MYPT1 Expression

Heart failure is associated with impairment in nitric oxide (NO) mediated vasodilatation, which has been demonstrated to result from a reduction in the relative expression of the leucine zipper positive (LZ+) isoform of the myosin targeting subunit (MYPT1) of myosin light chain phosphatase. Further,...

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Detalles Bibliográficos
Autores principales: Ararat, Erhan, Brozovich, Frank V.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2663051/
https://www.ncbi.nlm.nih.gov/pubmed/19357768
http://dx.doi.org/10.1371/journal.pone.0005144

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