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Negative Smad Expression and Regulation in the Developing Chick Limb

The inhibitory or negative Smads, Smad6 and Smad7, block TGFβ superfamily signals of both the BMP and TGFβ classes by antagonizing the intracellular signal transduction machinery. We report the cloning of one Smad6 and two Smad7 (Smad7a and Smad7b) chick homologs and their expression and regulation...

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Detalles Bibliográficos
Autores principales: Vargesson, Neil, Laufer, Ed
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2663054/
https://www.ncbi.nlm.nih.gov/pubmed/19352514
http://dx.doi.org/10.1371/journal.pone.0005173