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Effect of statin therapy on serum activity of proteinases and cytokines in patients with abdominal aortic aneurysm

BACKGROUND AND AIMS: Metalloproteinases (MMPs) are considered to be key enzymes in the pathogenesis of abdominal aortic aneurysms (AAA), with elevated levels in diseased aorta and in patient sera. Statins seem to exert an inhibitory effect on MMP activity in the aortic wall. No data exist on the eff...

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Detalles Bibliográficos
Autores principales: Muehling, Bernd, Oberhuber, Alexander, Schelzig, Hubert, Bischoff, Gisela, Marx, Nikolaus, Sunder-Plassmann, Ludger, Orend, Karl H
Formato: Texto
Lenguaje:English
Publicado: Dove Medical Press 2008
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2663432/
https://www.ncbi.nlm.nih.gov/pubmed/19337556