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Proinsulin C-peptide: Friend or foe in the development of diabetes-associated complications?

The proinsulin connecting peptide, C-peptide, is a cleavage product of insulin synthesis that is co-secreted with insulin by pancreatic β-cells following glucose stimulation. Recombinant insulin, used in the treatment of diabetes, lacks C-peptide and preclinical and clinical studies suggest that lac...

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Detalles Bibliográficos
Autores principales: Nordquist, Lina, Johansson, M
Formato: Texto
Lenguaje:English
Publicado: Dove Medical Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2663462/
https://www.ncbi.nlm.nih.gov/pubmed/19337542