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Proinsulin C-peptide: Friend or foe in the development of diabetes-associated complications?
The proinsulin connecting peptide, C-peptide, is a cleavage product of insulin synthesis that is co-secreted with insulin by pancreatic β-cells following glucose stimulation. Recombinant insulin, used in the treatment of diabetes, lacks C-peptide and preclinical and clinical studies suggest that lac...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
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Dove Medical Press
2008
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2663462/ https://www.ncbi.nlm.nih.gov/pubmed/19337542 |