ACE inhibition attenuates uremia-induced aortic valve thickening in a novel mouse model

BACKGROUND: We examined whether impaired renal function causes thickening of the aortic valve leaflets in hyperlipidemic apoE-knockout (apoE(-/-)) mice, and whether the putative effect on the aortic valves could be prevented by inhibiting the angiotensin-converting enzyme (ACE) with enalapril. METHO...

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Detalles Bibliográficos
Autores principales: Simolin, Mikko A, Pedersen, Tanja X, Bro, Susanne, Mäyränpää, Mikko I, Helske, Satu, Nielsen, Lars B, Kovanen, Petri T
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2663538/
https://www.ncbi.nlm.nih.gov/pubmed/19257900
http://dx.doi.org/10.1186/1471-2261-9-10

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2663538/
https://www.ncbi.nlm.nih.gov/pubmed/19257900
http://dx.doi.org/10.1186/1471-2261-9-10

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