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ACE inhibition attenuates uremia-induced aortic valve thickening in a novel mouse model
BACKGROUND: We examined whether impaired renal function causes thickening of the aortic valve leaflets in hyperlipidemic apoE-knockout (apoE(-/-)) mice, and whether the putative effect on the aortic valves could be prevented by inhibiting the angiotensin-converting enzyme (ACE) with enalapril. METHO...
| Autores principales: | , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2663538/ https://www.ncbi.nlm.nih.gov/pubmed/19257900 http://dx.doi.org/10.1186/1471-2261-9-10 |