Plausibility of stromal initiation of epithelial cancers without a mutation in the epithelium: a computer simulation of morphostats

BACKGROUND: There is experimental evidence from animal models favoring the notion that the disruption of interactions between stroma and epithelium plays an important role in the initiation of carcinogenesis. These disrupted interactions are hypothesized to be mediated by molecules, termed morphosta...

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Detalles Bibliográficos
Autores principales: Baker, Stuart G, Soto, Ana M, Sonnenschein, Carlos, Cappuccio, Antonio, Potter, John D, Kramer, Barnett S
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2663766/
https://www.ncbi.nlm.nih.gov/pubmed/19309499
http://dx.doi.org/10.1186/1471-2407-9-89

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2663766/
https://www.ncbi.nlm.nih.gov/pubmed/19309499
http://dx.doi.org/10.1186/1471-2407-9-89

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