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Plausibility of stromal initiation of epithelial cancers without a mutation in the epithelium: a computer simulation of morphostats
BACKGROUND: There is experimental evidence from animal models favoring the notion that the disruption of interactions between stroma and epithelium plays an important role in the initiation of carcinogenesis. These disrupted interactions are hypothesized to be mediated by molecules, termed morphosta...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2663766/ https://www.ncbi.nlm.nih.gov/pubmed/19309499 http://dx.doi.org/10.1186/1471-2407-9-89 |