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Integrated Functional, Gene Expression and Genomic Analysis for the Identification of Cancer Targets

The majority of new drug approvals for cancer are based on existing therapeutic targets. One approach to the identification of novel targets is to perform high-throughput RNA interference (RNAi) cellular viability screens. We describe a novel approach combining RNAi screening in multiple cell lines...

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Detalles Bibliográficos
Autores principales: Iorns, Elizabeth, Lord, Christopher J., Grigoriadis, Anita, McDonald, Sarah, Fenwick, Kerry, MacKay, Alan, Mein, Charles A., Natrajan, Rachael, Savage, Kay, Tamber, Narinder, Reis-Filho, Jorge S., Turner, Nicholas C., Ashworth, Alan
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2663812/
https://www.ncbi.nlm.nih.gov/pubmed/19357772
http://dx.doi.org/10.1371/journal.pone.0005120