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Integrated Functional, Gene Expression and Genomic Analysis for the Identification of Cancer Targets
The majority of new drug approvals for cancer are based on existing therapeutic targets. One approach to the identification of novel targets is to perform high-throughput RNA interference (RNAi) cellular viability screens. We describe a novel approach combining RNAi screening in multiple cell lines...
Autores principales: | Iorns, Elizabeth, Lord, Christopher J., Grigoriadis, Anita, McDonald, Sarah, Fenwick, Kerry, MacKay, Alan, Mein, Charles A., Natrajan, Rachael, Savage, Kay, Tamber, Narinder, Reis-Filho, Jorge S., Turner, Nicholas C., Ashworth, Alan |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2663812/ https://www.ncbi.nlm.nih.gov/pubmed/19357772 http://dx.doi.org/10.1371/journal.pone.0005120 |
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