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A Critical Role for CD8 T Cells in a Nonhuman Primate Model of Tuberculosis

The role of CD8 T cells in anti-tuberculosis immunity in humans remains unknown, and studies of CD8 T cell–mediated protection against tuberculosis in mice have yielded controversial results. Unlike mice, humans and nonhuman primates share a number of important features of the immune system that rel...

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Detalles Bibliográficos
Autores principales: Chen, Crystal Y., Huang, Dan, Wang, Richard C., Shen, Ling, Zeng, Gucheng, Yao, Shuyun, Shen, Yun, Halliday, Lisa, Fortman, Jeff, McAllister, Milton, Estep, Jim, Hunt, Robert, Vasconcelos, Daphne, Du, George, Porcelli, Steven A., Larsen, Michelle H., Jacobs, William R., Haynes, Barton F., Letvin, Norman L., Chen, Zheng W.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2663842/
https://www.ncbi.nlm.nih.gov/pubmed/19381260
http://dx.doi.org/10.1371/journal.ppat.1000392