Insights into the Regulation of TNF-α Production in Human Mononuclear Cells: The Effects of Non-Specific Phosphodiesterase Inhibition

OBJECTIVE: The objective of this study was to determine the effect of nonspecific phosphodiesterase inhibition on transcription factor activation and tumor necrosis factor-alpha (TNF-α) production in lipopolysaccharide (LPS)-stimulated human mononuclear cells. INTRODUCTION: The production of TNF-α f...

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Detalles Bibliográficos
Autores principales: Deree, Jessica, Martins, Joilson O., Melbostad, Heidi, Loomis, William H., Coimbra, Raul
Formato: Texto
Lenguaje:English
Publicado: Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo 2008
Materias:
Clinical Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2664230/
https://www.ncbi.nlm.nih.gov/pubmed/18568240
http://dx.doi.org/10.1590/S1807-59322008000300006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2664230/
https://www.ncbi.nlm.nih.gov/pubmed/18568240
http://dx.doi.org/10.1590/S1807-59322008000300006

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