High frequency of BRCA1, but not CHEK2 or NBS1 (NBN), founder mutations in Russian ovarian cancer patients

BACKGROUND: A significant portion of ovarian cancer (OC) cases is caused by germ-line mutations in BRCA1 or BRCA2 genes. BRCA testing is cheap in populations with founder effect and therefore recommended for all patients with OC diagnosis. Recurrent mutations constitute the vast majority of BRCA def...

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Detalles Bibliográficos
Autores principales: Suspitsin, Evgeny N, Sherina, Nathalia Yu, Ponomariova, Daria N, Sokolenko, Anna P, Iyevleva, Aglaya G, Gorodnova, Tatyana V, Zaitseva, Olga A, Yatsuk, Olga S, Togo, Alexandr V, Tkachenko, Nathalia N, Shiyanov, Grigory A, Lobeiko, Oksana S, Krylova, Nadezhda Yu, Matsko, Dmitry E, Maximov, Sergey Ya, Urmancheyeva, Adel F, Porhanova, Nathalia V, Imyanitov, Evgeny N
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2664323/
https://www.ncbi.nlm.nih.gov/pubmed/19338682
http://dx.doi.org/10.1186/1897-4287-7-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2664323/
https://www.ncbi.nlm.nih.gov/pubmed/19338682
http://dx.doi.org/10.1186/1897-4287-7-5

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