Cargando…
Amplification-free Illumina sequencing-library preparation facilitates improved mapping and assembly of GC-biased genomes
Amplification artifacts introduced during library preparation for the Illumina Genome Analyzer increase the likelihood that an appreciable proportion of these sequences will be duplicates, and cause an uneven distribution of read coverage across the targeted sequencing regions. As a consequence, the...
| Autores principales: | , , , , , |
|---|---|
| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
2009
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2664327/ https://www.ncbi.nlm.nih.gov/pubmed/19287394 http://dx.doi.org/10.1038/nmeth.1311 |