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Comparison of Proteomic and Transcriptomic Profiles in the Bronchial Airway Epithelium of Current and Never Smokers

BACKGROUND: Although prior studies have demonstrated a smoking-induced field of molecular injury throughout the lung and airway, the impact of smoking on the airway epithelial proteome and its relationship to smoking-related changes in the airway transcriptome are unclear. METHODOLOGY/PRINCIPAL FIND...

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Detalles Bibliográficos
Autores principales: Steiling, Katrina, Kadar, Aran Y., Bergerat, Agnes, Flanigon, James, Sridhar, Sriram, Shah, Vishal, Ahmad, Q. Rushdy, Brody, Jerome S., Lenburg, Marc E., Steffen, Martin, Spira, Avrum
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2664466/
https://www.ncbi.nlm.nih.gov/pubmed/19357784
http://dx.doi.org/10.1371/journal.pone.0005043