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Acid sphingomyelinase activity triggers microparticle release from glial cells

We have earlier shown that microglia, the immune cells of the CNS, release microparticles from cell plasma membrane after ATP stimulation. These vesicles contain and release IL-1β, a crucial cytokine in CNS inflammatory events. In this study, we show that microparticles are also released by astrocyt...

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Detalles Bibliográficos
Autores principales: Bianco, Fabio, Perrotta, Cristiana, Novellino, Luisa, Francolini, Maura, Riganti, Loredana, Menna, Elisabetta, Saglietti, Laura, Schuchman, Edward H, Furlan, Roberto, Clementi, Emilio, Matteoli, Michela, Verderio, Claudia
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2664656/
https://www.ncbi.nlm.nih.gov/pubmed/19300439
http://dx.doi.org/10.1038/emboj.2009.45