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Nonradioactive heteroduplex tracking assay for the detection of minority-variant chloroquine-resistant Plasmodium falciparum in Madagascar

BACKGROUND: Strains of Plasmodium falciparum genetically resistant to chloroquine (CQ) due to the presence of pfcrt 76T appear to have been recently introduced to the island of Madagascar. The prevalence of such resistant genotypes is reported to be low (< 3%) when evaluated by conventional PCR....

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Detalles Bibliográficos
Autores principales: Juliano, Jonathan J, Randrianarivelojosia, Milijaona, Ramarosandratana, Benjamin, Ariey, Frédéric, Mwapasa, Victor, Meshnick, Steven R
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2664821/
https://www.ncbi.nlm.nih.gov/pubmed/19291288
http://dx.doi.org/10.1186/1475-2875-8-47