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Nonradioactive heteroduplex tracking assay for the detection of minority-variant chloroquine-resistant Plasmodium falciparum in Madagascar
BACKGROUND: Strains of Plasmodium falciparum genetically resistant to chloroquine (CQ) due to the presence of pfcrt 76T appear to have been recently introduced to the island of Madagascar. The prevalence of such resistant genotypes is reported to be low (< 3%) when evaluated by conventional PCR....
Autores principales: | Juliano, Jonathan J, Randrianarivelojosia, Milijaona, Ramarosandratana, Benjamin, Ariey, Frédéric, Mwapasa, Victor, Meshnick, Steven R |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2664821/ https://www.ncbi.nlm.nih.gov/pubmed/19291288 http://dx.doi.org/10.1186/1475-2875-8-47 |
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