Rates of Spontaneous Cleavage of Glucose, Fructose, Sucrose, and Trehalose in Water, and the Catalytic Proficiencies of Invertase and Trehalas

[Image: see text] The half-lives for spontaneous hydrolysis of trehalose and sucrose at 25 °C are 6.6 × 10(6) years and 440 years. The half-lives for decomposition of the hydrolysis products glucose and fructose are 96 years and 70 days, respectively. Whereas sucrose and trehalose differ by a factor...

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Autores principales: Wolfenden, Richard, Yuan, Yang
Formato: Texto
Lenguaje:English
Publicado: American Chemical Society 2008
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2664835/
https://www.ncbi.nlm.nih.gov/pubmed/18505259
http://dx.doi.org/10.1021/ja802206s
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author Wolfenden, Richard
Yuan, Yang
author_facet Wolfenden, Richard
Yuan, Yang
author_sort Wolfenden, Richard
collection PubMed
description [Image: see text] The half-lives for spontaneous hydrolysis of trehalose and sucrose at 25 °C are 6.6 × 10(6) years and 440 years. The half-lives for decomposition of the hydrolysis products glucose and fructose are 96 years and 70 days, respectively. Whereas sucrose and trehalose differ by a factor of 15000 in their rates of uncatalyzed hydrolysis, the reactions catalyzed by invertase (EC 3.2.1.26) and trehalase (EC 3.2.1.28) proceed at similar rates. Accordingly, the attainments of invertase as a catalyst are modest, but the rate enhancement and catalytic proficiency produced by trehalase approach the high levels achieved by polysaccharide hydrolases.
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spelling pubmed-26648352009-04-06 Rates of Spontaneous Cleavage of Glucose, Fructose, Sucrose, and Trehalose in Water, and the Catalytic Proficiencies of Invertase and Trehalas Wolfenden, Richard Yuan, Yang J Am Chem Soc [Image: see text] The half-lives for spontaneous hydrolysis of trehalose and sucrose at 25 °C are 6.6 × 10(6) years and 440 years. The half-lives for decomposition of the hydrolysis products glucose and fructose are 96 years and 70 days, respectively. Whereas sucrose and trehalose differ by a factor of 15000 in their rates of uncatalyzed hydrolysis, the reactions catalyzed by invertase (EC 3.2.1.26) and trehalase (EC 3.2.1.28) proceed at similar rates. Accordingly, the attainments of invertase as a catalyst are modest, but the rate enhancement and catalytic proficiency produced by trehalase approach the high levels achieved by polysaccharide hydrolases. American Chemical Society 2008-05-28 2008-06-18 /pmc/articles/PMC2664835/ /pubmed/18505259 http://dx.doi.org/10.1021/ja802206s Text en Copyright © 2008 American Chemical Society http://pubs.acs.org This is an open-access article distributed under the ACS AuthorChoice Terms & Conditions. Any use of this article, must conform to the terms of that license which are available at http://pubs.acs.org. 40.75
spellingShingle Wolfenden, Richard
Yuan, Yang
Rates of Spontaneous Cleavage of Glucose, Fructose, Sucrose, and Trehalose in Water, and the Catalytic Proficiencies of Invertase and Trehalas
title Rates of Spontaneous Cleavage of Glucose, Fructose, Sucrose, and Trehalose in Water, and the Catalytic Proficiencies of Invertase and Trehalas
title_full Rates of Spontaneous Cleavage of Glucose, Fructose, Sucrose, and Trehalose in Water, and the Catalytic Proficiencies of Invertase and Trehalas
title_fullStr Rates of Spontaneous Cleavage of Glucose, Fructose, Sucrose, and Trehalose in Water, and the Catalytic Proficiencies of Invertase and Trehalas
title_full_unstemmed Rates of Spontaneous Cleavage of Glucose, Fructose, Sucrose, and Trehalose in Water, and the Catalytic Proficiencies of Invertase and Trehalas
title_short Rates of Spontaneous Cleavage of Glucose, Fructose, Sucrose, and Trehalose in Water, and the Catalytic Proficiencies of Invertase and Trehalas
title_sort rates of spontaneous cleavage of glucose, fructose, sucrose, and trehalose in water, and the catalytic proficiencies of invertase and trehalas
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2664835/
https://www.ncbi.nlm.nih.gov/pubmed/18505259
http://dx.doi.org/10.1021/ja802206s
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