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Heterochronic Shift in Hox-Mediated Activation of Sonic hedgehog Leads to Morphological Changes during Fin Development

We explored the molecular mechanisms of morphological transformations of vertebrate paired fin/limb evolution by comparative gene expression profiling and functional analyses. In this study, we focused on the temporal differences of the onset of Sonic hedgehog (Shh) expression in paired appendages a...

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Detalles Bibliográficos
Autores principales: Sakamoto, Koji, Onimaru, Koh, Munakata, Keijiro, Suda, Natsuno, Tamura, Mika, Ochi, Haruki, Tanaka, Mikiko
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2664896/
https://www.ncbi.nlm.nih.gov/pubmed/19365553
http://dx.doi.org/10.1371/journal.pone.0005121