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Heterochronic Shift in Hox-Mediated Activation of Sonic hedgehog Leads to Morphological Changes during Fin Development
We explored the molecular mechanisms of morphological transformations of vertebrate paired fin/limb evolution by comparative gene expression profiling and functional analyses. In this study, we focused on the temporal differences of the onset of Sonic hedgehog (Shh) expression in paired appendages a...
Autores principales: | Sakamoto, Koji, Onimaru, Koh, Munakata, Keijiro, Suda, Natsuno, Tamura, Mika, Ochi, Haruki, Tanaka, Mikiko |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2664896/ https://www.ncbi.nlm.nih.gov/pubmed/19365553 http://dx.doi.org/10.1371/journal.pone.0005121 |
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