Changes in Proteasome Structure and Function Caused by HAMLET in Tumor Cells

BACKGROUND: Proteasomes control the level of endogenous unfolded proteins by degrading them in the proteolytic core. Insufficient degradation due to altered protein structure or proteasome inhibition may trigger cell death. This study examined the proteasome response to HAMLET, a partially unfolded...

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Detalles Bibliográficos
Autores principales: Gustafsson, Lotta, Aits, Sonja, Önnerfjord, Patrik, Trulsson, Maria, Storm, Petter, Svanborg, Catharina
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2664966/
https://www.ncbi.nlm.nih.gov/pubmed/19365565
http://dx.doi.org/10.1371/journal.pone.0005229

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2664966/
https://www.ncbi.nlm.nih.gov/pubmed/19365565
http://dx.doi.org/10.1371/journal.pone.0005229

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