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The adhesion molecule L1 regulates transendothelial migration and trafficking of dendritic cells

The adhesion molecule L1, which is extensively characterized in the nervous system, is also expressed in dendritic cells (DCs), but its function there has remained elusive. To address this issue, we ablated L1 expression in DCs of conditional knockout mice. L1-deficient DCs were impaired in adhesion...

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Detalles Bibliográficos
Autores principales: Maddaluno, Luigi, Verbrugge, Sue Ellen, Martinoli, Chiara, Matteoli, Gianluca, Chiavelli, Andrea, Zeng, Yiping, Williams, Elizabeth D., Rescigno, Maria, Cavallaro, Ugo
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2664975/
https://www.ncbi.nlm.nih.gov/pubmed/19273627
http://dx.doi.org/10.1084/jem.20081211