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Modeling peptide fragmentation with dynamic Bayesian networks for peptide identification

Motivation: Tandem mass spectrometry (MS/MS) is an indispensable technology for identification of proteins from complex mixtures. Proteins are digested to peptides that are then identified by their fragmentation patterns in the mass spectrometer. Thus, at its core, MS/MS protein identification relie...

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Detalles Bibliográficos
Autores principales: Klammer, Aaron A., Reynolds, Sheila M., Bilmes, Jeff A., MacCoss, Michael J., Noble, William Stafford
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2665034/
https://www.ncbi.nlm.nih.gov/pubmed/18586734
http://dx.doi.org/10.1093/bioinformatics/btn189