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Pairwise statistical significance of local sequence alignment using multiple parameter sets and empirical justification of parameter set change penalty

BACKGROUND: Accurate estimation of statistical significance of a pairwise alignment is an important problem in sequence comparison. Recently, a comparative study of pairwise statistical significance with database statistical significance was conducted. In this paper, we extend the earlier work on pa...

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Detalles Bibliográficos
Autores principales: Agrawal, Ankit, Huang, Xiaoqiu
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2665049/
https://www.ncbi.nlm.nih.gov/pubmed/19344477
http://dx.doi.org/10.1186/1471-2105-10-S3-S1