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Annexin 2 Has a Dual Role as Regulator and Effector of v-Src in Cell Transformation

Cell transformation by v-Src involves rearrangement of the actin cytoskeleton, disassembly of focal adhesions, and the development of anchorage-independent growth. Here, we report that this is dependent on annexin 2, a v-Src substrate and calcium-dependent regulator of actin dynamics. Using a thermo...

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Detalles Bibliográficos
Autores principales: Hayes, Matthew J., Moss, Stephen E.
Formato: Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2665074/
https://www.ncbi.nlm.nih.gov/pubmed/19193640
http://dx.doi.org/10.1074/jbc.M807043200