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Molecular dissection of translation termination mechanism identifies two new critical regions in eRF1

Translation termination in eukaryotes is completed by two interacting factors eRF1 and eRF3. In Saccharomyces cerevisiae, these proteins are encoded by the genes SUP45 and SUP35, respectively. The eRF1 protein interacts directly with the stop codon at the ribosomal A-site, whereas eRF3—a GTPase prot...

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Detalles Bibliográficos
Autores principales: Hatin, Isabelle, Fabret, Celine, Rousset, Jean-Pierre, Namy, Olivier
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2665212/
https://www.ncbi.nlm.nih.gov/pubmed/19174561
http://dx.doi.org/10.1093/nar/gkp012