Cargando…

Molecular dissection of translation termination mechanism identifies two new critical regions in eRF1

Translation termination in eukaryotes is completed by two interacting factors eRF1 and eRF3. In Saccharomyces cerevisiae, these proteins are encoded by the genes SUP45 and SUP35, respectively. The eRF1 protein interacts directly with the stop codon at the ribosomal A-site, whereas eRF3—a GTPase prot...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hatin, Isabelle, Fabret, Celine, Rousset, Jean-Pierre, Namy, Olivier
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2009
Materias:	RNA
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2665212/ https://www.ncbi.nlm.nih.gov/pubmed/19174561 http://dx.doi.org/10.1093/nar/gkp012

Ejemplares similares

New insights into stop codon recognition by eRF1
por: Blanchet, Sandra, et al.
Publicado: (2015)

Translational accuracy of a tethered ribosome
por: Fabret, Celine, et al.
Publicado: (2021)

Translation termination depends on the sequential ribosomal entry of eRF1 and eRF3
por: Beißel, Christian, et al.
Publicado: (2019)

Nucleotide modifications in three functionally important regions of the Saccharomyces cerevisiae ribosome affect translation accuracy
por: Baudin-Baillieu, Agnès, et al.
Publicado: (2009)

Expression of the eRF1 translation termination factor is controlled by an autoregulatory circuit involving readthrough and nonsense-mediated decay in plants
por: Nyikó, Tünde, et al.
Publicado: (2017)

Divergent effects of translation termination factor eRF3A and nonsense-mediated mRNA decay factor UPF1 on the expression of uORF carrying mRNAs and ribosome protein genes
por: Aliouat, Affaf, et al.
Publicado: (2019)

A novel mutant of the Sup35 protein of Saccharomyces cerevisiae defective in translation termination and in GTPase activity still supports cell viability
por: Fabret, Céline, et al.
Publicado: (2008)

N-terminal region of Saccharomyces cerevisiae eRF3 is essential for the functioning of the eRF1/eRF3 complex beyond translation termination
por: Urakov, Valery N, et al.
Publicado: (2006)

Correction: A Viable Hypomorphic Allele of the Essential IMP3 Gene Reveals Novel Protein Functions in Saccharomyces cerevisiae
por: Cosnier, Bruno, et al.
Publicado: (2011)

A Viable Hypomorphic Allele of the Essential IMP3 Gene Reveals Novel Protein Functions in Saccharomyces cerevisiae
por: Cosnier, Bruno, et al.
Publicado: (2011)

Rab-GDI Complex Dissociation Factor Expressed through Translational Frameshifting in Filamentous Ascomycetes
por: Malagnac, Fabienne, et al.
Publicado: (2013)

Cryoelectron Microscopic Structures of Eukaryotic Translation Termination Complexes Containing eRF1-eRF3 or eRF1-ABCE1
por: Preis, Anne, et al.
Publicado: (2014)

Human nonsense-mediated mRNA decay factor UPF2 interacts directly with eRF3 and the SURF complex
por: López-Perrote, Andrés, et al.
Publicado: (2016)

Termination of translation in eukaryotes is mediated by the quaternary eRF1•eRF3•GTP•Mg(2+) complex. The biological roles of eRF3 and prokaryotic RF3 are profoundly distinct
por: Mitkevich, Vladimir A., et al.
Publicado: (2006)

The translational landscape of Arabidopsis mitochondria
por: Planchard, Noelya, et al.
Publicado: (2018)

A single methyltransferase YefA (RlmCD) catalyses both m(5)U747 and m(5)U1939 modifications in Bacillus subtilis 23S rRNA
por: Desmolaize, Benoit, et al.
Publicado: (2011)

Optimal Translational Termination Requires C4 Lysyl Hydroxylation of eRF1
por: Feng, Tianshu, et al.
Publicado: (2014)

Structure of the mammalian ribosomal pre-termination complex associated with eRF1•eRF3•GDPNP
por: des Georges, Amédée, et al.
Publicado: (2014)

Elongation factor eEF1B modulates functions of the release factors eRF1 and eRF3 and the efficiency of translation termination in yeast
por: Valouev, Igor A, et al.
Publicado: (2009)

A genetic approach for analyzing the co-operative function of the tRNA mimicry complex, eRF1/eRF3, in translation termination on the ribosome
por: Wada, Miki, et al.
Publicado: (2014)

Misdecoding of rare CGA codon by translation termination factors, eRF1/eRF3, suggests novel class of ribosome rescue pathway in S. cerevisiae
por: Wada, Miki, et al.
Publicado: (2018)

Studies on human eRF3-PABP interaction reveal the influence of eRF3a N-terminal glycin repeat on eRF3-PABP binding affinity and the lower affinity of eRF3a 12-GGC allele involved in cancer susceptibility
por: Jerbi, Soumaya, et al.
Publicado: (2016)

New insights into the incorporation of natural suppressor tRNAs at stop codons in Saccharomyces cerevisiae
por: Blanchet, Sandra, et al.
Publicado: (2014)

Translational control and Rho-dependent transcription termination are intimately linked in riboswitch regulation
por: Bastet, Laurène, et al.
Publicado: (2017)

Irregular G-quadruplexes Found in the Untranslated Regions of Human mRNAs Influence Translation
por: Bolduc, François, et al.
Publicado: (2016)

Identification of stop codon readthrough genes in Saccharomyces cerevisiae
por: Namy, Olivier, et al.
Publicado: (2003)

The terminal loop region controls microRNA processing by Drosha and Dicer
por: Zhang, Xiaoxiao, et al.
Publicado: (2010)

Selectivity of stop codon recognition in translation termination is modulated by multiple conformations of GTS loop in eRF1
por: Wong, Leo E., et al.
Publicado: (2012)

A genetic screen for terminator function in yeast identifies a role for a new functional domain in termination factor Nab3
por: Loya, Travis J., et al.
Publicado: (2012)

Precise quantification of translation inhibition by mRNA structures that overlap with the ribosomal footprint in N-terminal coding sequences
por: Espah Borujeni, Amin, et al.
Publicado: (2017)

Dynamics of release factor recycling during translation termination in bacteria
por: Prabhakar, Arjun, et al.
Publicado: (2023)

Coupled termination/reinitiation for translation of the downstream open reading frame B of the prototypic hypovirus CHV1-EP713
por: Guo, Li-hua, et al.
Publicado: (2009)

GTP-dependent structural rearrangement of the eRF1:eRF3 complex and eRF3 sequence motifs essential for PABP binding
por: Kononenko, Artem V., et al.
Publicado: (2010)

Translational Recoding and RNA Modifications
por: Namy, Olivier, et al.
Publicado: (2005)

Poly(A) binding protein, C-terminally truncated by the hepatitis A virus proteinase 3C, inhibits viral translation
por: Zhang, Bo, et al.
Publicado: (2007)

An intact ribose moiety at A2602 of 23S rRNA is key to trigger peptidyl-tRNA hydrolysis during translation termination
por: Amort, Melanie, et al.
Publicado: (2007)

A specific role for the C-terminal region of the Poly(A)-binding protein in mRNA decay
por: Simón, Ernesto, et al.
Publicado: (2007)

An unstructured 5′-coding region of the prfA mRNA is required for efficient translation
por: Loh, Edmund, et al.
Publicado: (2012)

Antagonistic factors control the unproductive splicing of SC35 terminal intron
por: Dreumont, Natacha, et al.
Publicado: (2010)

Rescue of non-sense mutated p53 tumor suppressor gene by aminoglycosides
por: Floquet, Célia, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_pc8co0fvdbanpisajnv0p65k0n