Mitochondrial DNA level, but not active replicase, is essential for Caenorhabditis elegans development

A number of studies showed that the development and the lifespan of Caenorhabditis elegans is dependent on mitochondrial function. In this study, we addressed the role of mitochondrial DNA levels and mtDNA maintenance in development of C. elegans by analyzing deletion mutants for mitochondrial polym...

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Detalles Bibliográficos
Autores principales: Bratic, Ivana, Hench, Jürgen, Henriksson, Johan, Antebi, Adam, Bürglin, Thomas R, Trifunovic, Aleksandra
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2665216/
https://www.ncbi.nlm.nih.gov/pubmed/19181702
http://dx.doi.org/10.1093/nar/gkp018

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2665216/
https://www.ncbi.nlm.nih.gov/pubmed/19181702
http://dx.doi.org/10.1093/nar/gkp018

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