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Mitochondrial DNA level, but not active replicase, is essential for Caenorhabditis elegans development
A number of studies showed that the development and the lifespan of Caenorhabditis elegans is dependent on mitochondrial function. In this study, we addressed the role of mitochondrial DNA levels and mtDNA maintenance in development of C. elegans by analyzing deletion mutants for mitochondrial polym...
Autores principales: | Bratic, Ivana, Hench, Jürgen, Henriksson, Johan, Antebi, Adam, Bürglin, Thomas R, Trifunovic, Aleksandra |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2665216/ https://www.ncbi.nlm.nih.gov/pubmed/19181702 http://dx.doi.org/10.1093/nar/gkp018 |
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