A synthetic snRNA m(3)G-CAP enhances nuclear delivery of exogenous proteins and nucleic acids

Accessing the nucleus through the surrounding membrane poses one of the major obstacles for therapeutic molecules large enough to be excluded due to nuclear pore size limits. In some therapeutic applications the large size of some nucleic acids, like plasmid DNA, hampers their access to the nuclear...

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Detalles Bibliográficos
Autores principales: Moreno, Pedro M. D., Wenska, Malgorzata, Lundin, Karin E., Wrange, Örjan, Strömberg, Roger, Smith, C. I. Edvard
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Chemistry and Synthetic Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2665231/
https://www.ncbi.nlm.nih.gov/pubmed/19208638
http://dx.doi.org/10.1093/nar/gkp048

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2665231/
https://www.ncbi.nlm.nih.gov/pubmed/19208638
http://dx.doi.org/10.1093/nar/gkp048

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