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A synthetic snRNA m(3)G-CAP enhances nuclear delivery of exogenous proteins and nucleic acids
Accessing the nucleus through the surrounding membrane poses one of the major obstacles for therapeutic molecules large enough to be excluded due to nuclear pore size limits. In some therapeutic applications the large size of some nucleic acids, like plasmid DNA, hampers their access to the nuclear...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2665231/ https://www.ncbi.nlm.nih.gov/pubmed/19208638 http://dx.doi.org/10.1093/nar/gkp048 |