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U1-independent pre-mRNA splicing contributes to the regulation of alternative splicing

U1 snRNP plays a crucial role in the 5′ splice site recognition during splicing. Here we report the first example of naturally occurring U1-independent U2-type splicing in humans. The U1 components were not included in the pre-spliceosomal E complex formed on the human F1γ (hF1γ) intron 9 in vitro....

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Detalles Bibliográficos
Autores principales: Fukumura, Kazuhiro, Taniguchi, Ichiro, Sakamoto, Hiroshi, Ohno, Mutsuhito, Inoue, Kunio
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2665233/
https://www.ncbi.nlm.nih.gov/pubmed/19190090
http://dx.doi.org/10.1093/nar/gkp050