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JWA regulates XRCC1 and functions as a novel base excision repair protein in oxidative-stress-induced DNA single-strand breaks

JWA was recently demonstrated to be involved in cellular responses to environmental stress including oxidative stress. Although it was found that JWA protected cells from reactive oxygen species-induced DNA damage, upregulated base excision repair (BER) protein XRCC1 and downregulated PARP-1, the mo...

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Detalles Bibliográficos
Autores principales: Wang, Shouyu, Gong, Zhenghua, Chen, Rui, Liu, Yunru, Li, Aiping, Li, Gang, Zhou, Jianwei
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2665235/
https://www.ncbi.nlm.nih.gov/pubmed/19208635
http://dx.doi.org/10.1093/nar/gkp054