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Characterization of DNA polymerase X from Thermus thermophilus HB8 reveals the POLXc and PHP domains are both required for 3′–5′ exonuclease activity

The X-family DNA polymerases (PolXs) comprise a highly conserved DNA polymerase family found in all kingdoms. Mammalian PolXs are known to be involved in several DNA-processing pathways including repair, but the cellular functions of bacterial PolXs are less known. Many bacterial PolXs have a polyme...

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Detalles Bibliográficos
Autores principales: Nakane, Shuhei, Nakagawa, Noriko, Kuramitsu, Seiki, Masui, Ryoji
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2665239/
https://www.ncbi.nlm.nih.gov/pubmed/19211662
http://dx.doi.org/10.1093/nar/gkp064