Cargando…

Mechanism of Genomic Instability in Cells Infected with the High-Risk Human Papillomaviruses

In HPV–related cancers, the “high-risk” human papillomaviruses (HPVs) are frequently found integrated into the cellular genome. The integrated subgenomic HPV fragments express viral oncoproteins and carry an origin of DNA replication that is capable of initiating bidirectional DNA re-replication in...

Descripción completa

Detalles Bibliográficos
Autores principales: Kadaja, Meelis, Isok-Paas, Helen, Laos, Triin, Ustav, Ene, Ustav, Mart
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2666264/
https://www.ncbi.nlm.nih.gov/pubmed/19390600
http://dx.doi.org/10.1371/journal.ppat.1000397