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Mechanism of Genomic Instability in Cells Infected with the High-Risk Human Papillomaviruses
In HPV–related cancers, the “high-risk” human papillomaviruses (HPVs) are frequently found integrated into the cellular genome. The integrated subgenomic HPV fragments express viral oncoproteins and carry an origin of DNA replication that is capable of initiating bidirectional DNA re-replication in...
Autores principales: | Kadaja, Meelis, Isok-Paas, Helen, Laos, Triin, Ustav, Ene, Ustav, Mart |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2666264/ https://www.ncbi.nlm.nih.gov/pubmed/19390600 http://dx.doi.org/10.1371/journal.ppat.1000397 |
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