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Inhibitory Activity of Myelin-Associated Glycoprotein on Sensory Neurons Is Largely Independent of NgR1 and NgR2 and Resides within Ig-Like Domains 4 and 5

Myelin-associated glycoprotein (MAG) is a sialic acid binding Ig-like lectin (Siglec) which has been characterized as potent myelin-derived inhibitor of neurite outgrowth. Two members of the Nogo-receptor (NgR) family, NgR1 and NgR2, have been identified as neuronal binding proteins of MAG. In addit...

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Detalles Bibliográficos
Autores principales: Wörter, Verena, Schweigreiter, Rüdiger, Kinzel, Bernd, Mueller, Matthias, Barske, Carmen, Böck, Günther, Frentzel, Stefan, Bandtlow, Christine E.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2666269/
https://www.ncbi.nlm.nih.gov/pubmed/19367338
http://dx.doi.org/10.1371/journal.pone.0005218