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Human CtIP Mediates Cell Cycle Control of DNA End Resection and Double Strand Break Repair

In G(0) and G(1), DNA double strand breaks are repaired by nonhomologous end joining, whereas in S and G(2), they are also repaired by homologous recombination. The human CtIP protein controls double strand break (DSB) resection, an event that occurs effectively only in S/G(2) and that promotes homo...

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Detalles Bibliográficos
Autores principales: Huertas, Pablo, Jackson, Stephen P.
Formato: Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2666608/
https://www.ncbi.nlm.nih.gov/pubmed/19202191
http://dx.doi.org/10.1074/jbc.M808906200