Photo-activation of the hydrophobic probe iodonaphthylazide in cells alters membrane protein function leading to cell death

BACKGROUND: Photo-activation of the hydrophobic membrane probe 1, 5 iodonaphthylazide (INA) by irradiation with UV light (310–380 nm) results in the covalent modification of transmembrane anchors of membrane proteins. This unique selectivity of INA towards the transmembrane anchor has been exploited...

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Detalles Bibliográficos
Autores principales: Viard, Mathias, Garg, Himanshu, Blumenthal, Robert, Raviv, Yossef
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2666636/
https://www.ncbi.nlm.nih.gov/pubmed/19323821
http://dx.doi.org/10.1186/1471-2121-10-21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2666636/
https://www.ncbi.nlm.nih.gov/pubmed/19323821
http://dx.doi.org/10.1186/1471-2121-10-21

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