Cargando…
Photo-activation of the hydrophobic probe iodonaphthylazide in cells alters membrane protein function leading to cell death
BACKGROUND: Photo-activation of the hydrophobic membrane probe 1, 5 iodonaphthylazide (INA) by irradiation with UV light (310–380 nm) results in the covalent modification of transmembrane anchors of membrane proteins. This unique selectivity of INA towards the transmembrane anchor has been exploited...
| Autores principales: | , , , |
|---|---|
| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2009
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2666636/ https://www.ncbi.nlm.nih.gov/pubmed/19323821 http://dx.doi.org/10.1186/1471-2121-10-21 |