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Synthetic RGDS peptide attenuates lipopolysaccharide-induced pulmonary inflammation by inhibiting integrin signaled MAP kinase pathways

BACKGROUND: Synthetic peptides containing the RGD sequence inhibit integrin-related functions in different cell systems. Here, we investigated the effects of synthetic Arg-Gly-Asp-Ser (RGDS) peptide on key inflammatory responses to intratracheal (i.t.) lipopolysaccharide (LPS) treatment and on the i...

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Detalles Bibliográficos
Autores principales: Moon, Changsuk, Han, Jeong Ran, Park, Hyun-Jung, Hah, Jong Sik, Kang, Jihee Lee
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2666640/
https://www.ncbi.nlm.nih.gov/pubmed/19272161
http://dx.doi.org/10.1186/1465-9921-10-18